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Amino Acids 53 , 9931009 (2021)

It improves immune responses to changing conditions and increases overall immune system robustness and effectiveness

Mice with signs of unrelated illness, abnormal baseline renal function, or technical failure during surgery/crystal injection were excluded from analysis

Additionally, GCN2 expression in macrophages and MDSCs promotes their suppressive function, restraining antitumor immunity in mouse models of colon cancer and melanoma [153]

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